Restalyne is developed by The Cleveland Clinic.

What development phase is Restalyne in?

Restalyne is FDA-approved (marketed).

Last reviewed 2026-04-20 · How we verify

Restalyne

The Cleveland Clinic · FDA-approved active Small molecule Quality 1/100

At a glance

Generic name	Restalyne
Also known as	Hyaluronan; Hyaluronate Sodium; Hyaluronic Acid
Sponsor	The Cleveland Clinic
Modality	Small molecule
Therapeutic area	Other
Phase	FDA-approved

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Rejuvenation of the Lower Eyelid Using a Combination of Two Hyaluronic Acid Fillers - a Pilot Study (PHASE4)
A Clinical Study Comparing Restylane® Silk and Belotero Balance® for the Treatment of Superficial, Vertical Perioral Lines (PHASE4)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Restalyne CI brief — competitive landscape report
Restalyne updates RSS · CI watch RSS
The Cleveland Clinic portfolio CI