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regional block
A regional block is a local anesthetic technique that numbs a specific region of the body by injecting anesthetic agents near nerves that supply that area.
A regional block is a local anesthetic technique that numbs a specific region of the body by injecting anesthetic agents near nerves that supply that area. Used for Surgical anesthesia for regional procedures, Acute and chronic pain management, Perioperative analgesia.
At a glance
| Generic name | regional block |
|---|---|
| Sponsor | OrthoCarolina Research Institute, Inc. |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | FDA-approved |
Mechanism of action
Regional blocks work by delivering local anesthetic drugs (such as lidocaine or bupivacaine) to nerve bundles or plexuses, temporarily blocking nerve conduction and preventing pain sensation in the targeted anatomical region. This approach provides localized anesthesia without affecting consciousness, making it useful for surgical procedures, pain management, and diagnostic procedures in specific body areas.
Approved indications
- Surgical anesthesia for regional procedures
- Acute and chronic pain management
- Perioperative analgesia
Common side effects
- Temporary numbness or weakness in the blocked region
- Bruising or hematoma at injection site
- Nerve injury (rare)
- Local anesthetic toxicity (rare)
Key clinical trials
- Effect of Scalp Block on Intraoperative Hemodynamics and Postoperative Pain in Craniotomy Patients" (NA)
- Intervention Programme for Seniors (NA)
- Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome (PHASE2)
- Sphenopalatine Ganglion Block for Post-Dural Puncture Headache: A Pilot Randomised Controlled Trial (NA)
- Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty (NA)
- Ischemic Preconditioning in Resistance Exercise in Older Women (NA)
- Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion (EARLY_PHASE1)
- mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- regional block CI brief — competitive landscape report
- regional block updates RSS · CI watch RSS
- OrthoCarolina Research Institute, Inc. portfolio CI