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Regenerative tissue matrix
A regenerative tissue matrix that provides a scaffold for tissue repair and regeneration by delivering bioactive components and supporting cellular growth.
A regenerative tissue matrix that provides a scaffold for tissue repair and regeneration by delivering bioactive components and supporting cellular growth. Used for Tissue repair and regeneration (specific indications vary by product formulation).
At a glance
| Generic name | Regenerative tissue matrix |
|---|---|
| Also known as | AlloDerm RTM, BioHorizons |
| Sponsor | University of Louisville |
| Drug class | Regenerative medicine product / Tissue engineering scaffold |
| Modality | Biologic |
| Therapeutic area | Regenerative Medicine / Wound Care / Tissue Repair |
| Phase | FDA-approved |
Mechanism of action
Regenerative tissue matrices are decellularized or engineered extracellular matrix (ECM) products that serve as biological scaffolds to promote tissue healing and regeneration. They contain growth factors, structural proteins, and other bioactive molecules that facilitate cell migration, differentiation, and tissue remodeling. These matrices are designed to be resorbed and replaced by native tissue over time.
Approved indications
- Tissue repair and regeneration (specific indications vary by product formulation)
Common side effects
- Inflammatory response
- Infection
- Delayed healing
Key clinical trials
- Regenerative Collagen Scaffold for Breast Volume Restoration After Breast Cancer Excision (NA)
- Effectiveness and Safety of X A-DERM™ Microsurfaced Acellular Dermal Matrix for Wound Healing After MOHS Surgery (NA)
- Myriad™ Augmented Soft Tissue Reconstruction Registry
- Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects (NA)
- Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative (PHASE4)
- Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft (PHASE4)
- Inclusion Body Myositis Treatment With Celution Processed Adipose Derived Regenerative Cells (NA)
- Microderm for Root Coverage Procedures (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Regenerative tissue matrix CI brief — competitive landscape report
- Regenerative tissue matrix updates RSS · CI watch RSS
- University of Louisville portfolio CI