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recombinant FSH
recombinant FSH is a Small molecule drug developed by University of Colorado, Denver. It is currently FDA-approved. Also known as: rFHS, Gonal-f, Puregon, Gonal-F.
Recombinant FSH is used to treat conditions such as female infertility, infertility, controlled ovarian hyperstimulation, multifollicular stimulation, and non-obstructive azoospermia. It belongs to the class of hydrolytic enzymes and works by hydrolyzing hyaluronic acid, according to its mechanism of action.
At a glance
| Generic name | recombinant FSH |
|---|---|
| Also known as | rFHS, Gonal-f, Puregon, Gonal-F, Follitrophin-beta |
| Sponsor | University of Colorado, Denver |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- PPOS vs GnRH Antagonist in Ovarian Stimulation (ProGanOS Study) (NA)
- Risk of Infertility Related to Adjuvant Chemotherapy for Early Breast Cancer: Oocyte/Embryo Cryopreservation (NA)
- A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA) (PHASE3)
- Exogenous Progesterone as Ovulation Trigger (PHASE4)
- Study on the Pharmacokinetics and Safety of QL1012D and Gonal-F® in Healthy Female Volunteers (PHASE1)
- IVF Outcomes With Time-Lapse Culture: Comparison Between PPOS and GnRH Antagonist Protocols (NA)
- rFSH vs rFSH+rLH in Dydrogesterone-Based Progestin Protocol: A Prospective Study
- Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- recombinant FSH CI brief — competitive landscape report
- recombinant FSH updates RSS · CI watch RSS
- University of Colorado, Denver portfolio CI
Frequently asked questions about recombinant FSH
What is recombinant FSH?
Who makes recombinant FSH?
Is recombinant FSH also known as anything else?
What development phase is recombinant FSH in?
Related
- Manufacturer: University of Colorado, Denver — full pipeline
- Also known as: rFHS, Gonal-f, Puregon, Gonal-F, Follitrophin-beta
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing