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Rate Control
Rate Control is a therapeutic approach designed to manage heart rate in patients with atrial fibrillation by slowing atrioventricular node conduction.
Rate Control is a therapeutic approach designed to manage heart rate in patients with atrial fibrillation by slowing atrioventricular node conduction. Used for Atrial fibrillation with rapid ventricular response.
At a glance
| Generic name | Rate Control |
|---|---|
| Also known as | Beta-blocker, Calcium channel blockers, Digoxin, Toprol, Tenormin |
| Sponsor | Icahn School of Medicine at Mount Sinai |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 3 |
Mechanism of action
Rate control therapy aims to reduce the ventricular response rate in atrial fibrillation patients to improve symptoms and reduce cardiovascular complications, without necessarily converting the arrhythmia to normal sinus rhythm. This is typically achieved through pharmacological agents that slow conduction through the AV node, such as beta-blockers, calcium channel blockers, or digoxin, or through device-based interventions.
Approved indications
- Atrial fibrillation with rapid ventricular response
Common side effects
Key clinical trials
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- SMART-VERAPAF: Self-MAnagement and Random Therapy With VERApamil or Metoprolol in Paroxysmal Atrial Fibrillation (PHASE4)
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Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |