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Radiotracer Injection

Massachusetts General Hospital · Phase 2 active Small molecule ✓ Verified May 2026 Quality 18/100

Radiotracer Injection is a Small molecule drug developed by Massachusetts General Hospital. It is currently in Phase 2 development. Also known as: [11C]APP311, [11C]UCB-J.

Radiotracer injection is a method used in positron emission tomography (PET) imaging for detecting various types of cancer, including endometrial and ovarian cancers, as seen in the study "4FMFES-PET Imaging of Endometrial and Ovarian Cancers" (NCT04823065). The specific radiotracer used in this study is 11C-sarcosine, which is injected into the body to help identify cancerous tissues.

Likelihood of approval
15.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameRadiotracer Injection
Also known as[11C]APP311, [11C]UCB-J
SponsorMassachusetts General Hospital
ModalitySmall molecule
PhasePhase 2

Approved indications

No approved indications tracked.

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Radiotracer Injection

What is Radiotracer Injection?

Radiotracer Injection is a Small molecule drug developed by Massachusetts General Hospital.

Who makes Radiotracer Injection?

Radiotracer Injection is developed by Massachusetts General Hospital (see full Massachusetts General Hospital pipeline at /company/massachusetts-general-hospital).

Is Radiotracer Injection also known as anything else?

Radiotracer Injection is also known as [11C]APP311, [11C]UCB-J.

What development phase is Radiotracer Injection in?

Radiotracer Injection is in Phase 2.

What are the side effects of Radiotracer Injection?

Common side effects of Radiotracer Injection include Headache, Flushing, Dyspnoea, Dizziness, Chest discomfort, Nausea.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing