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Radiofrequency ablation with radiotherapy
Radiofrequency ablation with radiotherapy involves using heat generated by radiofrequency waves to destroy cancer cells, followed by radiation therapy to kill any remaining cancer cells.
Radiofrequency ablation with radiotherapy involves using heat generated by radiofrequency waves to destroy cancer cells, followed by radiation therapy to kill any remaining cancer cells. Used for Treatment of liver cancer, Treatment of kidney cancer.
At a glance
| Generic name | Radiofrequency ablation with radiotherapy |
|---|---|
| Sponsor | Guangxi Medical University |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
Radiofrequency ablation is a minimally invasive procedure that uses a special probe to generate heat and destroy cancer cells. The heat generated by the radiofrequency waves causes the cancer cells to die, and the radiation therapy that follows helps to kill any remaining cancer cells. This combination of treatments can be effective in treating certain types of cancer.
Approved indications
- Treatment of liver cancer
- Treatment of kidney cancer
Common side effects
- Pain
- Fatigue
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Hemorrhage
- Infection
- Bleeding
- Thrombosis
Key clinical trials
- Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors
- Software-Aided Imaging (Morfeus) for Confirming Tumor Coverage With Ablation in Patients With Liver Tumors, the COVER-ALL Study (PHASE2)
- IMMULAB - Immunotherapy With Pembrolizumab in Combination With Local Ablation in Hepatocellular Carcinoma (HCC) (PHASE2)
- A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy
- Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer (PHASE2)
- Systemic Therapy With or Without Local Consolidative Therapy in Treating Patients With Oligometastatic Solid Tumor (PHASE2)
- Assess the Efficacy of Pembrolizumab Plus Radiotherapy or Ablation in Metastatic Colorectal Cancer Patients (PHASE2)
- Radiofrequency Ablation/Bone Augmentation + Radiotherapy vs Radiotherapy Alone (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |