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Rabbit antithymocyte globulin
Rabbit antithymocyte globulin is a Small molecule drug developed by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. It is currently FDA-approved. Also known as: Thymoglobulin, rATG, rATG, thymoglobulin, Thymoglobuline.
Rabbit antithymocyte globulin is used to treat various conditions, including kidney transplantation, renal transplant recipients, liver failure, hematologic malignancy, and bone marrow transplant. Its mechanism of action is unknown, but it is known to be a type of immunoglobulin, specifically a human vaccinia immune globulin.
At a glance
| Generic name | Rabbit antithymocyte globulin |
|---|---|
| Also known as | Thymoglobulin, rATG, rATG, thymoglobulin, Thymoglobuline, RATG |
| Sponsor | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation (PHASE2, PHASE3)
- Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis (PHASE4)
- Uterine Transplantation and Pregnancy Induction in Women Affected by Absolute Uterine Infertility (NA)
- Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients (PHASE2)
- Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia (PHASE2)
- A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes (PHASE1, PHASE2)
- Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders (PHASE2)
- Immune Tolerance Induction After Liver Transplantation (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Rabbit antithymocyte globulin CI brief — competitive landscape report
- Rabbit antithymocyte globulin updates RSS · CI watch RSS
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins portfolio CI
Frequently asked questions about Rabbit antithymocyte globulin
What is Rabbit antithymocyte globulin?
Who makes Rabbit antithymocyte globulin?
Is Rabbit antithymocyte globulin also known as anything else?
What development phase is Rabbit antithymocyte globulin in?
Related
- Manufacturer: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — full pipeline
- Also known as: Thymoglobulin, rATG, rATG, thymoglobulin, Thymoglobuline, RATG
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing