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Qvar
Qvar is an inhaled corticosteroid that reduces airway inflammation by binding to glucocorticoid receptors in lung tissue.
Qvar is an inhaled corticosteroid that reduces airway inflammation by binding to glucocorticoid receptors in lung tissue. Used for Asthma maintenance treatment, Asthma prophylaxis.
At a glance
| Generic name | Qvar |
|---|---|
| Also known as | beclomethasone dipropionate HFA |
| Sponsor | Teva Branded Pharmaceutical Products R&D, Inc. |
| Drug class | Inhaled corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Respiratory/Pulmonology |
| Phase | FDA-approved |
Mechanism of action
Beclomethasone dipropionate, the active ingredient in Qvar, is a corticosteroid that suppresses inflammatory responses in the airways by activating glucocorticoid receptors. This leads to decreased production of inflammatory mediators, reduced mucus secretion, and decreased airway hyperresponsiveness. The hydrofluoroalkane (HFA) propellant formulation provides improved lung deposition compared to older chlorofluorocarbon formulations.
Approved indications
- Asthma maintenance treatment
- Asthma prophylaxis
Common side effects
- Tremor
- Headache
- Nervousness
- Oral candidiasis
- Throat irritation
Key clinical trials
- Study in Adult Patients With Moderate to Severe Asthma (PHASE3)
- Fixed Triple Inhaled Combination in Asthmatic Patients in a Real-life Setting (STRENGTH)
- Fixed Triple Inhaled Combination in Asthmatic Patients in a Real-life Setting
- Directed Topical Drug Delivery for Treatment for PASC Hyposmia (PHASE2)
- Efficacy and Safety of CHF 1535 200/6µg in Not Adequately Controlled Asthmatic Patients (PHASE3)
- Triple Therapy in Real-life: Impact on Adherence and Health Status (TRITRIAL)
- Effects of Beclometasone Dipropionate/Formoterol Fumarate Via NEXT(Haler) in a Real-world Study on Asthma Control
- Biomarkers for Predicting the Response to Inhaled Corticosteroid in Patients With Chronic Cough. (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |