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quadrivalent human papillomavirus vaccine

University of Pittsburgh · FDA-approved active Biologic

quadrivalent human papillomavirus vaccine is a vaccine Biologic drug developed by University of Pittsburgh. It is currently FDA-approved for Prevention of cervical cancer caused by HPV types 16 and 18, Prevention of genital warts caused by HPV types 6 and 11, Prevention of anal cancer and other HPV-related cancers. Also known as: Gardasil.

The vaccine stimulates the immune system to produce antibodies against four types of human papillomavirus (HPV types 6, 11, 16, and 18) to prevent infection and associated diseases.

The vaccine stimulates the immune system to produce antibodies against four types of human papillomavirus (HPV types 6, 11, 16, and 18) to prevent infection and associated diseases. Used for Prevention of cervical cancer caused by HPV types 16 and 18, Prevention of genital warts caused by HPV types 6 and 11, Prevention of anal cancer and other HPV-related cancers.

At a glance

Generic namequadrivalent human papillomavirus vaccine
Also known asGardasil
SponsorUniversity of Pittsburgh
Drug classvaccine
TargetHuman papillomavirus types 6, 11, 16, 18
ModalityBiologic
Therapeutic areaOncology / Immunology
PhaseFDA-approved

Mechanism of action

The quadrivalent HPV vaccine contains virus-like particles (VLPs) derived from the major capsid protein of four HPV types. These VLPs are non-infectious but structurally similar to natural HPV virions, triggering a robust humoral immune response that generates neutralizing antibodies. This antibody response provides protection against infection by these HPV types, preventing cervical cancer, genital warts, and other HPV-related malignancies.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about quadrivalent human papillomavirus vaccine

What is quadrivalent human papillomavirus vaccine?

quadrivalent human papillomavirus vaccine is a vaccine drug developed by University of Pittsburgh, indicated for Prevention of cervical cancer caused by HPV types 16 and 18, Prevention of genital warts caused by HPV types 6 and 11, Prevention of anal cancer and other HPV-related cancers.

How does quadrivalent human papillomavirus vaccine work?

The vaccine stimulates the immune system to produce antibodies against four types of human papillomavirus (HPV types 6, 11, 16, and 18) to prevent infection and associated diseases.

What is quadrivalent human papillomavirus vaccine used for?

quadrivalent human papillomavirus vaccine is indicated for Prevention of cervical cancer caused by HPV types 16 and 18, Prevention of genital warts caused by HPV types 6 and 11, Prevention of anal cancer and other HPV-related cancers.

Who makes quadrivalent human papillomavirus vaccine?

quadrivalent human papillomavirus vaccine is developed and marketed by University of Pittsburgh (see full University of Pittsburgh pipeline at /company/university-of-pittsburgh).

Is quadrivalent human papillomavirus vaccine also known as anything else?

quadrivalent human papillomavirus vaccine is also known as Gardasil.

What drug class is quadrivalent human papillomavirus vaccine in?

quadrivalent human papillomavirus vaccine belongs to the vaccine class. See all vaccine drugs at /class/vaccine.

What development phase is quadrivalent human papillomavirus vaccine in?

quadrivalent human papillomavirus vaccine is FDA-approved (marketed).

What are the side effects of quadrivalent human papillomavirus vaccine?

Common side effects of quadrivalent human papillomavirus vaccine include Injection site pain, Injection site swelling, Injection site erythema, Fever, Nausea.

What does quadrivalent human papillomavirus vaccine target?

quadrivalent human papillomavirus vaccine targets Human papillomavirus types 6, 11, 16, 18 and is a vaccine.

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