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Quadratus lumborum block
Quadratus lumborum block is a Small molecule drug developed by University Tunis El Manar. It is currently FDA-approved for Perioperative analgesia for abdominal and flank surgery, Postoperative pain management for lower abdominal procedures, Chronic pain management in the lower back and flank region. Also known as: QLB, QL Block, QL, saline.
A regional anesthesia technique that blocks the quadratus lumborum muscle plane to provide analgesia to the lower abdomen and flank by interrupting nerve conduction.
A regional anesthesia technique that blocks the quadratus lumborum muscle plane to provide analgesia to the lower abdomen and flank by interrupting nerve conduction. Used for Perioperative analgesia for abdominal and flank surgery, Postoperative pain management for lower abdominal procedures, Chronic pain management in the lower back and flank region.
At a glance
| Generic name | Quadratus lumborum block |
|---|---|
| Also known as | QLB, QL Block, QL, saline |
| Sponsor | University Tunis El Manar |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | FDA-approved |
Mechanism of action
The quadratus lumborum block (QLB) is a peripheral nerve block that targets the plane between the quadratus lumborum muscle and adjacent fasciae in the retroperitoneal space. Local anesthetic is deposited in this anatomical plane to block branches of the thoracolumbar nerves (T6-L1), providing somatic and visceral analgesia to the lower abdomen, flank, and lower back regions. This technique is used perioperatively to reduce pain and opioid requirements.
Approved indications
- Perioperative analgesia for abdominal and flank surgery
- Postoperative pain management for lower abdominal procedures
- Chronic pain management in the lower back and flank region
Common side effects
- Local anesthetic systemic toxicity
- Hematoma or bleeding at injection site
- Infection at injection site
- Nerve injury
- Peritoneal puncture
Key clinical trials
- Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty (NA)
- mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery (NA)
- Anterior QLB for PCNL (NA)
- Analgesic Comparison of Transversus Fascial Plane and Quadratus Lumborum Blocks in Pediatric Urogenital Procedures (NA)
- Erector Spinae Plane Versus Quadratus Lumborum Blocks for Pain Management After Total Abdominal Hysterectomy (NA)
- Effect of the Quadratus Lumborum Block Versus the Lumbar Plexus for Spiral Thighplasty Surgery (NA)
- QIPB in Inguinal Hernia (NA)
- mTLIP vs QIPB for Postoperative Analgesia After Lumbar Instrumentation Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Quadratus lumborum block CI brief — competitive landscape report
- Quadratus lumborum block updates RSS · CI watch RSS
- University Tunis El Manar portfolio CI
Frequently asked questions about Quadratus lumborum block
What is Quadratus lumborum block?
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Related
- Manufacturer: University Tunis El Manar — full pipeline
- Therapeutic area: All drugs in Anesthesia/Pain Management
- Indication: Drugs for Perioperative analgesia for abdominal and flank surgery
- Indication: Drugs for Postoperative pain management for lower abdominal procedures
- Indication: Drugs for Chronic pain management in the lower back and flank region
- Also known as: QLB, QL Block, QL, saline
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing