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Pyridoxine plus prednisolone
Pyridoxine (vitamin B6) supports immune function and nervous system health while prednisolone suppresses inflammatory and immune responses through glucocorticoid receptor activation.
Pyridoxine (vitamin B6) supports immune function and nervous system health while prednisolone suppresses inflammatory and immune responses through glucocorticoid receptor activation. Used for Autoimmune or inflammatory conditions (specific indication not publicly detailed).
At a glance
| Generic name | Pyridoxine plus prednisolone |
|---|---|
| Sponsor | Lady Hardinge Medical College |
| Drug class | Combination therapy (vitamin B6 + corticosteroid) |
| Modality | Small molecule |
| Therapeutic area | Immunology / Rheumatology / Neurology |
| Phase | Phase 3 |
Mechanism of action
Pyridoxine is an essential cofactor for numerous enzymatic reactions involved in immune cell function and neurotransmitter synthesis. Prednisolone is a corticosteroid that binds glucocorticoid receptors to reduce inflammation, suppress immune cell proliferation, and decrease production of pro-inflammatory cytokines. The combination likely aims to provide nutritional support while managing inflammatory or autoimmune conditions.
Approved indications
- Autoimmune or inflammatory conditions (specific indication not publicly detailed)
Common side effects
- Hyperglycemia
- Immunosuppression / increased infection risk
- Insomnia
- Mood changes
- Gastrointestinal upset
- Peripheral neuropathy (pyridoxine at high doses)
Key clinical trials
- Adjunctive Doxycycline for Central Nervous System Tuberculosis (PHASE2)
- Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-Syndrome (PHASE3)
- Addition of Pyridoxine to Prednisolone in Infantile Spasms (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Pyridoxine plus prednisolone CI brief — competitive landscape report
- Pyridoxine plus prednisolone updates RSS · CI watch RSS
- Lady Hardinge Medical College portfolio CI