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Pyridoxine Hydrochloride (PYRIDOXINE)
Pyridoxine Hydrochloride (generic name: PYRIDOXINE) is a Vitamin C [EPC] Small molecule drug developed by Pfizer. It is currently FDA-approved (first approved 1993) for Breastfeeding (mother), Drug-Induced Pyridoxine Deficiency, Pregnancy, function.
Pyridoxine Hydrochloride is a small molecule with the synonyms including Pyridoxine. It is used in various clinical trials, including those for conditions such as fibroids, stroke, and stress, often in combination with other interventions like dydrogesterone or folic acid.
At a glance
| Generic name | PYRIDOXINE |
|---|---|
| Sponsor | Pfizer |
| Drug class | Vitamin C [EPC] |
| Target | Cystathionine beta-synthase |
| Modality | Small molecule |
| Therapeutic area | Metabolic |
| Phase | FDA-approved |
| First approval | 1993 |
Approved indications
- Breastfeeding (mother)
- Drug-Induced Pyridoxine Deficiency
- Pregnancy, function
- Pyridoxine-Dependent Seizure
- Vitamin B6 deficiency
Boxed warnings
- WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
Common side effects
- Paresthesia
- Somnolence
- Low serum folic acid levels
Key clinical trials
- The Acute Effects of Onnit Alpha Brain on Cognition and Mood States (NA)
- An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM (PHASE3)
- The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms (NA)
- Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion (EARLY_PHASE1)
- Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism (NA)
- The Effects of Vitamin B6 Supplementation on Pain Thresholds and Tolerance (PHASE1)
- A Study Evaluating Quality of Life Parameters Following Use of Emergen-C (PHASE4)
- The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Pyridoxine Hydrochloride CI brief — competitive landscape report
- Pyridoxine Hydrochloride updates RSS · CI watch RSS
- Pfizer portfolio CI
Frequently asked questions about Pyridoxine Hydrochloride
What is Pyridoxine Hydrochloride?
What is Pyridoxine Hydrochloride used for?
Who makes Pyridoxine Hydrochloride?
What is the generic name of Pyridoxine Hydrochloride?
What drug class is Pyridoxine Hydrochloride in?
When was Pyridoxine Hydrochloride approved?
What development phase is Pyridoxine Hydrochloride in?
What are the side effects of Pyridoxine Hydrochloride?
What does Pyridoxine Hydrochloride target?
Related
- Drug class: All Vitamin C [EPC] drugs
- Target: All drugs targeting Cystathionine beta-synthase
- Manufacturer: Pfizer — full pipeline
- Therapeutic area: All drugs in Metabolic
- Indication: Drugs for Breastfeeding (mother)
- Indication: Drugs for Drug-Induced Pyridoxine Deficiency
- Indication: Drugs for Pregnancy, function
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing