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Propolis 20%
Propolis 20% is a natural bee product that exerts antimicrobial, anti-inflammatory, and antioxidant effects through its polyphenolic and flavonoid constituents.
Propolis 20% is a natural bee product that exerts antimicrobial, anti-inflammatory, and antioxidant effects through its polyphenolic and flavonoid constituents. Used for Wound healing and tissue repair, Oral health and periodontal conditions, Antimicrobial and anti-inflammatory topical applications.
At a glance
| Generic name | Propolis 20% |
|---|---|
| Also known as | Bee glue |
| Sponsor | Dow University of Health Sciences |
| Drug class | Natural product/botanical extract |
| Modality | Small molecule |
| Therapeutic area | Dermatology, Wound Care, Oral Health |
| Phase | FDA-approved |
Mechanism of action
Propolis contains bioactive compounds including flavonoids, phenolic acids, and essential oils that inhibit bacterial and fungal growth, reduce inflammatory cytokine production, and scavenge free radicals. These properties make it useful in wound healing, oral health, and immune support applications. The exact molecular targets vary depending on the specific bioactive components present in the formulation.
Approved indications
- Wound healing and tissue repair
- Oral health and periodontal conditions
- Antimicrobial and anti-inflammatory topical applications
Common side effects
- Allergic contact dermatitis
- Sensitization in allergic individuals
- Local irritation at application site
Key clinical trials
- Assessing the Impact of Herbal Supplement on Fatigue and Disease Activity in SLE: Results From an 8-Week Randomized Trial (NA)
- Effects of Propolis Flavonoids on TLR4 Signaling and Inflammation in Human PDLSCs In Vitro
- A Randomized Controlled Study on the Effect of MRJPs on Improving Ovarian Function and Endometrial Receptivity (NA)
- "Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds" (NA)
- Clinical and Radiographic Outcomes of Class II Furcation Defects Management Using Propolis: A Case Series (EARLY_PHASE1)
- Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in LSTR (NA)
- Role of Propolis Endodontic Irrigant on Post-Operative Pain (PHASE3)
- Comparative Evaluation of Propolis Mouthwash With 0.2% Chlorhexidine Mouthwash in Improving the Periodontitis (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Propolis 20% CI brief — competitive landscape report
- Propolis 20% updates RSS · CI watch RSS
- Dow University of Health Sciences portfolio CI