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Propofol + analgesic drug
Propofol is a sedative-hypnotic agent that acts on the central nervous system to induce and maintain anesthesia, while the analgesic component provides pain relief.
Propofol is a sedative-hypnotic agent that acts on the central nervous system to induce and maintain anesthesia, while the analgesic component provides pain relief. Used for General anesthesia, Sedation for short procedures.
At a glance
| Generic name | Propofol + analgesic drug |
|---|---|
| Sponsor | University Hospital, Brest |
| Drug class | Sedative-hypnotic |
| Target | GABA receptor |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 3 |
Mechanism of action
Propofol works by enhancing the inhibitory neurotransmission mediated by GABA, a major inhibitory neurotransmitter in the brain. The analgesic component may work through various mechanisms, including the inhibition of pain signaling pathways in the spinal cord and brain.
Approved indications
- General anesthesia
- Sedation for short procedures
Common side effects
- Respiratory depression
- Hypotension
- Nausea and vomiting
- Headache
- Dizziness
Key clinical trials
- Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery (PHASE1)
- Equivalent MAC in General Anesthesia
- General Anesthesia and General Anesthesia Combined With Thoracic Epidural Anesthesia (NA)
- A Comparison of Remimazolam Besylate and Propofol Sedation in Patients Undergoing Colonoscopic Polypectomy (PHASE4)
- qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery (NA)
- Opioid-Free vs Opioid-Based Anesthesia in Bariatric Surgery (NA)
- Magnesium Sulfate Versus Other Anesthesia Drugs to Reduce Agitation After Adenotonsillectomy in Pediatric Patients (NA)
- Efficacy and Safety of Anricofen Combined With Ciprofol for Deep Sedation in Elderly Patients Undergoing ERCP (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Propofol + analgesic drug CI brief — competitive landscape report
- Propofol + analgesic drug updates RSS · CI watch RSS
- University Hospital, Brest portfolio CI