Last reviewed · How we verify
probiotic mixture
A probiotic mixture restores beneficial bacterial populations in the gut microbiome to promote immune homeostasis and intestinal barrier function.
A probiotic mixture restores beneficial bacterial populations in the gut microbiome to promote immune homeostasis and intestinal barrier function. Used for Gastrointestinal disorders (specific indication under investigation in phase 3 trial).
At a glance
| Generic name | probiotic mixture |
|---|---|
| Sponsor | Hadassah Medical Organization |
| Drug class | Probiotic |
| Modality | Small molecule |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
Probiotic mixtures contain live beneficial bacteria that colonize the gastrointestinal tract, competing with pathogenic organisms and producing metabolites that strengthen the intestinal epithelial barrier. These organisms modulate the gut-associated lymphoid tissue and systemic immune responses, potentially reducing inflammation and improving mucosal immunity. The specific strains and their synergistic effects depend on the formulation composition.
Approved indications
- Gastrointestinal disorders (specific indication under investigation in phase 3 trial)
Common side effects
- Gastrointestinal disturbance (bloating, gas, mild diarrhea)
- Abdominal discomfort
Key clinical trials
- Assessment of the Effects of Probiotic Supplementation on Gut Microbiota Composition and Short-chain Fatty Acid Production in Frail Elderly Patients Receiving Home Enteral Nutrition With an Oligomeric Formula. (NA)
- An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System (NA)
- The Effect of Probiotic Supplementation on the Exercise Performance of Long-distance Runners. (NA)
- The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III (PHASE3)
- Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy Subjects (NA)
- Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial (PHASE2)
- Oral-Spray Bacillus Spore Probiotics for Periodontal Disease Prevention and Supprotive Treatment in the Elderly (NA)
- Effects of Saccharomyces Boulardii CNCM I-745 on Antibiotic-Associated Perturbation in Children Treated for Acute Respiratory Infections (RESTORE Study) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- probiotic mixture CI brief — competitive landscape report
- probiotic mixture updates RSS · CI watch RSS
- Hadassah Medical Organization portfolio CI