Last reviewed · How we verify
PreviDent Varnish
PreviDent Varnish is a topical fluoride varnish that strengthens tooth enamel and prevents dental caries by forming a protective fluoride-rich layer on tooth surfaces.
PreviDent Varnish is a topical fluoride varnish that strengthens tooth enamel and prevents dental caries by forming a protective fluoride-rich layer on tooth surfaces. Used for Dental caries prevention in children and adults, Remineralization of early enamel lesions.
At a glance
| Generic name | PreviDent Varnish |
|---|---|
| Also known as | Colgate PreviDent varnish ,product DI number: 00038341330937 |
| Sponsor | King Abdulaziz University |
| Drug class | Topical fluoride agent |
| Target | Tooth enamel (hydroxyapatite) |
| Modality | Small molecule |
| Therapeutic area | Dental/Preventive Medicine |
| Phase | FDA-approved |
Mechanism of action
The varnish delivers high concentrations of fluoride directly to tooth enamel, promoting remineralization and inhibiting demineralization caused by acid-producing bacteria. This creates a barrier that reduces cavity formation and can help arrest early-stage carious lesions. The varnish formulation allows for prolonged contact time between fluoride and tooth surfaces, enhancing its preventive efficacy.
Approved indications
- Dental caries prevention in children and adults
- Remineralization of early enamel lesions
Common side effects
- Mild tooth staining or discoloration
- Temporary fluorosis (with excessive ingestion)
- Mild gum irritation
Key clinical trials
- Preventing Early Childhood Caries With a Silver Diamine Fluoride Gel (PHASE2)
- Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin Hypersensitivity (NA)
- Traditional vs. Minimally Invasive Decay Treatments in Primary Molars: An 18-month Split-mouth Randomized Study (NA)
- Effects of Different Remineralization Agents on the Progression of Non-Cavitated Approximal Carious Lesions in Primary Teeth: A Randomized Clinical Trial (NA)
- Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children (NA)
- Effect Of Silverdiamine Fluoride Gel, Sodium Fluoride With CPP-ACP, APF On Early Childhood Caries - A Randomised Controlled Trial (PHASE2)
- Minimally Invasive Protocols for the Treatment and Control of Caries Lesions in Children and Adolescents (NA)
- Clinical Efficacy of Using Bioactive Desensitizer Gel (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PreviDent Varnish CI brief — competitive landscape report
- PreviDent Varnish updates RSS · CI watch RSS
- King Abdulaziz University portfolio CI