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Preserved Bimatoprost 0.01%

Universitaire Ziekenhuizen KU Leuven · FDA-approved active Small molecule

Bimatoprost is a prostaglandin F analog that increases uveoscleral outflow of aqueous humor to reduce intraocular pressure.

Bimatoprost is a prostaglandin F analog that increases uveoscleral outflow of aqueous humor to reduce intraocular pressure. Used for Open-angle glaucoma, Ocular hypertension.

At a glance

Generic namePreserved Bimatoprost 0.01%
Also known asBIMMD, Lumigan 0.01 %
SponsorUniversitaire Ziekenhuizen KU Leuven
Drug classProstaglandin F analog
TargetProstaglandin F receptor (FP receptor)
ModalitySmall molecule
Therapeutic areaOphthalmology
PhaseFDA-approved

Mechanism of action

Bimatoprost binds to prostaglandin F (FP) receptors on the ciliary muscle and trabecular meshwork, enhancing drainage of aqueous humor through the uveoscleral (unconventional) pathway. This increased outflow reduces intraocular pressure, making it effective for glaucoma and ocular hypertension. The preserved formulation contains antimicrobial preservatives to maintain sterility.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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