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Premixed bioceramic MTA
Premixed bioceramic MTA is a biocompatible calcium silicate-based cement that sets through hydration to form a hard matrix, used primarily as a root canal sealer and repair material in endodontic procedures.
Premixed bioceramic MTA is a biocompatible calcium silicate-based cement that sets through hydration to form a hard matrix, used primarily as a root canal sealer and repair material in endodontic procedures. Used for Root canal obturation and sealing, Periapical surgery and repair, Pulp capping and pulpotomy.
At a glance
| Generic name | Premixed bioceramic MTA |
|---|---|
| Also known as | Neoputty |
| Sponsor | Sarah Abdelbar Mahmoud |
| Modality | Small molecule |
| Therapeutic area | Dentistry / Endodontics |
| Phase | Phase 3 |
Mechanism of action
Bioceramic MTA (Mineral Trioxide Aggregate) is a premixed formulation combining calcium silicates, bismuth oxide, and other bioactive components. Upon contact with moisture, it undergoes hydration and sets to form a dense, biocompatible structure that promotes periapical healing and provides an effective seal against bacterial microleakage. The material exhibits antimicrobial properties and stimulates hard tissue formation through release of calcium ions.
Approved indications
- Root canal obturation and sealing
- Periapical surgery and repair
- Pulp capping and pulpotomy
- Perforation repair in endodontic treatment
Common side effects
- Discoloration of tooth structure
- Difficulty in removal if needed
- Allergic reaction (rare)
Key clinical trials
- Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis (NA)
- A Comparison of Outcome of Pulpotomy on Immature Permanent Molars Between Different Calcium Silicate-based Materials : a 12 Months Clinical Study (NA)
- Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy (NA)
- Clinical and Radiographic Evaluation of Three Biomimetic Materials in Pulp Therapy of Immature Young Permanent Teeth "A Randomized Controlled Clinical Trial" (PHASE3)
- Evaluation of Guided Endodontic Microsurgery and Two Different Retrograde Filling Materials (NA)
- Effectiveness of Premixed Bioactive Bioceramic MTA (Neo-Putty®) in Pulpotomies Primary Teeth
- Premixed Bioceramic Putty as an Apical Plug in Immature Anterior Permanent Teeth (NA)
- Clinical and Radiographic Evaluation of Vital Pulpotomy Techniques in Primary Molars Using of Premixed Bioactive Bioceramic MTA (Neo-putty) as a Novel Pulpotomy Medication Versus Formocresol (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |