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Prednisone 1 week
Prednisone 1 week is a Corticosteroid (glucocorticoid) Small molecule drug developed by Xinqiao Hospital of Chongqing. It is currently FDA-approved for Acute inflammatory conditions (non-specific short course), Autoimmune disorders, Allergic reactions. Also known as: Glucocorticoid.
Prednisone is a corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
Prednisone is a corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production. Used for Acute inflammatory conditions (non-specific short course), Autoimmune disorders, Allergic reactions.
At a glance
| Generic name | Prednisone 1 week |
|---|---|
| Also known as | Glucocorticoid |
| Sponsor | Xinqiao Hospital of Chongqing |
| Drug class | Corticosteroid (glucocorticoid) |
| Target | Glucocorticoid receptor (GR) |
| Modality | Small molecule |
| Therapeutic area | Immunology / Rheumatology / General anti-inflammatory |
| Phase | FDA-approved |
Mechanism of action
Prednisone acts as a glucocorticoid receptor agonist, translocating to the nucleus to modulate gene expression of inflammatory mediators. It decreases production of cytokines (IL-1, IL-6, TNF-α), reduces immune cell activation and proliferation, and stabilizes lysosomal membranes to limit inflammatory cell degranulation. The 1-week course indicates short-term anti-inflammatory or immunosuppressive therapy for acute conditions.
Approved indications
- Acute inflammatory conditions (non-specific short course)
- Autoimmune disorders
- Allergic reactions
- Asthma exacerbations
- Rheumatoid arthritis flares
Common side effects
- Insomnia
- Increased appetite
- Mood changes (irritability, anxiety)
- Hyperglycemia
- Gastrointestinal upset
- Headache
- Hypertension
Key clinical trials
- Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma (PHASE3)
- A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss (PHASE2)
- Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity (PHASE2)
- A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer (PHASE1, PHASE2)
- A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer (PHASE2)
- Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL (NA)
- Chidamide Combination With R-mini CHOP Followed by Chidamide+CD20 Maintenance in Elderly Newly Diagnosed MYC/BCL2+ DLBCL (PHASE2)
- Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Prednisone 1 week CI brief — competitive landscape report
- Prednisone 1 week updates RSS · CI watch RSS
- Xinqiao Hospital of Chongqing portfolio CI
Frequently asked questions about Prednisone 1 week
What is Prednisone 1 week?
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Related
- Drug class: All Corticosteroid (glucocorticoid) drugs
- Target: All drugs targeting Glucocorticoid receptor (GR)
- Manufacturer: Xinqiao Hospital of Chongqing — full pipeline
- Therapeutic area: All drugs in Immunology / Rheumatology / General anti-inflammatory
- Indication: Drugs for Acute inflammatory conditions (non-specific short course)
- Indication: Drugs for Autoimmune disorders
- Indication: Drugs for Allergic reactions
- Also known as: Glucocorticoid
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing