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Pre-Quit Nicotine Patch
Delivers nicotine transdermally to reduce withdrawal symptoms and cravings during smoking cessation.
Delivers nicotine transdermally to reduce withdrawal symptoms and cravings during smoking cessation. Used for Smoking cessation aid.
At a glance
| Generic name | Pre-Quit Nicotine Patch |
|---|---|
| Sponsor | University of Wisconsin, Madison |
| Drug class | Nicotine replacement therapy (NRT) |
| Target | Nicotinic acetylcholine receptors |
| Modality | Small molecule |
| Therapeutic area | Smoking Cessation / Addiction Medicine |
| Phase | FDA-approved |
Mechanism of action
The patch provides a steady, controlled release of nicotine through the skin, bypassing the rapid peaks and valleys of cigarette smoking. This maintains adequate nicotine levels to suppress withdrawal symptoms and reduce the reinforcing effects of smoking, allowing users to gradually taper nicotine doses. The transdermal route avoids the addictive delivery kinetics of inhaled nicotine while supporting behavioral cessation efforts.
Approved indications
- Smoking cessation aid
Common side effects
- Skin irritation at patch site
- Insomnia
- Vivid dreams or nightmares
- Headache
- Nausea
- Dizziness
Key clinical trials
- Exenatide for Smoking Cessation and Prevention of Weight Gain (PHASE2)
- Smoking Cessation and Menstrual Cycle Phase (PHASE4)
- Varenicline for Smoking Reduction in Veterans Not Ready To Quit (PHASE4)
- Smart Olfaction App to Reduce Relapse (EARLY_PHASE1)
- My Path to Quit Tobacco (PHASE4)
- Reward Sensitivity and Pharmacotherapy for Smoking Cessation (PHASE4)
- Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV (NA)
- Physical Activity in Promoting Smoking Cessation in African Americans (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Pre-Quit Nicotine Patch CI brief — competitive landscape report
- Pre-Quit Nicotine Patch updates RSS · CI watch RSS
- University of Wisconsin, Madison portfolio CI