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Povidone-Iodine-Alcohol
Povidone-iodine-alcohol is a topical antiseptic that kills microorganisms through the oxidizing and protein-denaturing properties of iodine combined with the antimicrobial and drying effects of alcohol.
Povidone-iodine-alcohol is a topical antiseptic that kills microorganisms through the oxidizing and protein-denaturing properties of iodine combined with the antimicrobial and drying effects of alcohol. Used for Skin antisepsis and disinfection prior to surgery or medical procedures, Wound disinfection and minor cut/abrasion treatment.
At a glance
| Generic name | Povidone-Iodine-Alcohol |
|---|---|
| Sponsor | Poitiers University Hospital |
| Drug class | Topical antiseptic |
| Modality | Small molecule |
| Therapeutic area | Dermatology / Infection Prevention |
| Phase | FDA-approved |
Mechanism of action
Povidone-iodine is a complex of iodine and povidone that releases free iodine, which penetrates microbial cell walls and denatures proteins, effectively killing bacteria, viruses, fungi, and some protozoa. The addition of alcohol enhances antimicrobial efficacy, accelerates drying, and improves skin penetration. This combination is commonly used for skin antisepsis and wound disinfection.
Approved indications
- Skin antisepsis and disinfection prior to surgery or medical procedures
- Wound disinfection and minor cut/abrasion treatment
Common side effects
- Skin irritation or burning sensation
- Allergic contact dermatitis (iodine sensitivity)
- Drying of skin
Key clinical trials
- Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy (NA)
- CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee (NA)
- Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip Surgeries (PHASE3)
- Management of Acute Appendicitis Pain in the Emergency Department
- Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients
- The Effect of High-thoracic Erector Spinae Plane Block on Postoperative Pain and Diaphragmatic Function in Posterior Cervical Spine Surgery (PHASE3)
- Investigation of the Effect of Central Sensitization (CS) on Steroid Injection Response in Rotator Cuff Lesion (NA)
- Investigating Pre-Procedural Anxiety and Effect of Analgesia on Intrauterine Device Placement and Endometrial Biopsy (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Povidone-Iodine-Alcohol CI brief — competitive landscape report
- Povidone-Iodine-Alcohol updates RSS · CI watch RSS
- Poitiers University Hospital portfolio CI