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Povidone-Iodine 5%
Povidone-iodine is an antiseptic that releases iodine to kill microorganisms by oxidizing and disrupting their cellular components.
Povidone-iodine is an antiseptic that releases iodine to kill microorganisms by oxidizing and disrupting their cellular components. Used for Skin antisepsis and wound disinfection, Oral and pharyngeal antisepsis, Preoperative skin preparation.
At a glance
| Generic name | Povidone-Iodine 5% |
|---|---|
| Also known as | Betadine |
| Sponsor | Norwegian University of Science and Technology |
| Drug class | Antiseptic/disinfectant |
| Modality | Small molecule |
| Therapeutic area | Dermatology/Infection Control |
| Phase | FDA-approved |
Mechanism of action
Povidone-iodine is a complex of iodine with polyvinylpyrrolidone (povidone) that acts as a broad-spectrum antimicrobial agent. The iodine component penetrates microbial cell walls and membranes, oxidizing proteins and nucleic acids, thereby inactivating bacteria, viruses, fungi, and protozoa. The povidone carrier provides sustained iodine release and improved stability.
Approved indications
- Skin antisepsis and wound disinfection
- Oral and pharyngeal antisepsis
- Preoperative skin preparation
Common side effects
- Skin irritation or contact dermatitis
- Iodine hypersensitivity reactions
- Staining of skin and clothing
Key clinical trials
- Durability of Three Monthly Loading Doses With Faricimab in Treatment-naïve Neovascular Age-related Macular Degeneration
- Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder (NA)
- Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip Surgeries (PHASE3)
- The Additive Effect of Exercise in Addition to Corticosteroid Injection in Plantar Fasciitis (NA)
- The Efficacy of Wet Cupping Therapy on Cerebral Oxygenation (NA)
- Management of Acute Appendicitis Pain in the Emergency Department
- Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block (NA)
- INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Povidone-Iodine 5% CI brief — competitive landscape report
- Povidone-Iodine 5% updates RSS · CI watch RSS
- Norwegian University of Science and Technology portfolio CI