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Vinyl Alcohol Polymer (POLYVINYL ALCOHOL)
Polyvinyl alcohol works by forming a protective barrier on the surface of the eye to help repair and maintain the tear film.
Polyvinyl alcohol (PVA), also known as polyvinyl alcohol polymer, is a synthetic polymer used in ophthalmic applications. It is used to treat red eye and tear film insufficiency by providing a protective barrier for the eye. PVA is a small molecule modality, but its commercial status and pharmacokinetic properties are not well-documented. It is currently owned by a pharmaceutical company, but the exact details are not publicly available. PVA is FDA-approved for its indicated uses.
At a glance
| Generic name | POLYVINYL ALCOHOL |
|---|---|
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | discontinued |
Mechanism of action
Imagine your eye's surface is like a delicate skin that needs to be protected and moisturized. Polyvinyl alcohol helps to create a shield that prevents further irritation and damage, allowing the eye to heal and recover. This protective barrier also helps to maintain the balance of the tear film, which is essential for clear vision and eye health.
Approved indications
- Red eye
- Tear film insufficiency
Common side effects
Key clinical trials
- Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy (NA)
- CECT Features of MVI Predict Response to TACE Plus TKI in Intermediate-stage HCC
- Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen Block (NA)
- Adjuvant TACE in HCC With High-risk Recurrence Factors (PHASE3)
- A Multicenter, Open-Label, Non-Comparative Study of the Safety and Contraceptive Efficacy of the Woman's Condom (NA)
- Phase 1 Study of Intravaginal KB15A (PHASE1)
- Photorefractive Keratectomy (PRK) : Comparison of Corneal Haze Between Two Modes of De-epithelialisation (Laser Versus Manual Alcohol) (NA)
- Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Vinyl Alcohol Polymer CI brief — competitive landscape report
- Vinyl Alcohol Polymer updates RSS · CI watch RSS