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Polyethoxylated Sorbitan Monooleate (POLYSORBATE 80)
POLYSORBATE 80, a marketed polyethoxylated sorbitan monooleate, is positioned in the redness relief segment of the ophthalmic market. Its key strength lies in its mechanism of action, which reduces the surface tension of tears to promote an even distribution and maintenance of a healthy tear film. The primary risk is the key composition patent expiry in 2028, which could lead to increased competition from generics.
At a glance
| Generic name | POLYSORBATE 80 |
|---|---|
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Approved indications
- Redness relief
- Burning and irritation relief
- Protection against further irritation
Common side effects
Key clinical trials
- Moxetumomab Pasudotox for Advanced Hairy Cell Leukemia (PHASE3)
- Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults (PHASE1)
- DaxibotulinumtoxinA for Blepharospasm (PHASE2)
- Safety and Efficacy of Faricimab in Patients With NPDR (PHASE2)
- Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants (PHASE3)
- Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD) (PHASE2)
- Effectiveness of Vitamin b12 Versus Kenalog on Traumatic Ulcer Associated With Orthodontic Treatment (NA)
- Study of Intravenous ZMA001 in Healthy Subjects (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Polyethoxylated Sorbitan Monooleate CI brief — competitive landscape report
- Polyethoxylated Sorbitan Monooleate updates RSS · CI watch RSS