Last reviewed · How we verify
Polyethylene Glycol afternoon
Polyethylene Glycol works by increasing the amount of water in the stool to make it easier to pass.
Polyethylene Glycol works by increasing the amount of water in the stool to make it easier to pass. Used for Treatment of constipation.
At a glance
| Generic name | Polyethylene Glycol afternoon |
|---|---|
| Also known as | GoLytely |
| Sponsor | Cleveland Clinic Florida |
| Drug class | Osmotic laxative |
| Modality | Small molecule |
| Therapeutic area | Gastrointestinal |
| Phase | Phase 3 |
Mechanism of action
Polyethylene Glycol is an osmotic laxative that helps to soften and increase the bulk of stool, making it easier to pass through the digestive system. This is achieved by increasing the amount of water in the stool, which helps to stimulate bowel movements and relieve constipation.
Approved indications
- Treatment of constipation
Common side effects
- Abdominal cramping
- Diarrhea
- Flatulence
- Nausea
Key clinical trials
- Combination of Lactulose and Polyethylene Glycol Electrolytes Powder (PEG-ELS) for Bowel Preparation in Type II Diabetes Mellitus Patients (NA)
- Fecal Microbiota Transplantation by Oral Capsules for Hepatic Encephalopathy Treatment (PHASE1)
- Short-term Effects of Bowel Preparation on Gut Microbiome in Patients Undergoing Endoscopic Colon Polypectomy (PHASE4)
- Efficacy, Safety and Tolerability of Different Bowel Preparation Before Colonoscopy in Children Over 2 Years Old (NA)
- The Effect of a Predictive Model of Bowel Preparation Based on Procedure-related Factors (NA)
- Prepackaged Nutritional Formulations Versus Restricted Diet for Bowel Preparation (NA)
- Comparison of Two Preparations for the Study of the Colon Through Colonoscopy
- Study of the Efficacy and Safety of Quiklean® and Klean-Prep With Dulcolax® for the Bowel Preparation Prior to Colonoscopy (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Polyethylene Glycol afternoon CI brief — competitive landscape report
- Polyethylene Glycol afternoon updates RSS · CI watch RSS
- Cleveland Clinic Florida portfolio CI