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4L PEG
4L PEG is a Osmotic laxative Small molecule drug developed by Changhai Hospital. It is currently FDA-approved. Also known as: polyethylene glycol.
4L PEG, marketed by Changhai Hospital, is an osmotic laxative used for bowel evacuation. Its key strength lies in its mechanism of action, which effectively draws water into the colon to facilitate cleansing. The primary risk is the patent expiry in 2028, which could lead to increased competition from generics.
At a glance
| Generic name | 4L PEG |
|---|---|
| Also known as | polyethylene glycol |
| Sponsor | Changhai Hospital |
| Drug class | Osmotic laxative |
| Target | Colon |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- Impact of Chewing Gum on Bowel Preparation in Patients Undergoing Colonoscopy (NA)
- Effect of Non-invasive Neuromodulation on the Quality of Intestinal Cleansing (NA)
- Efficacy, Tolerance and Safety of Split Dose Bowel Preparation for Colonoscopy: 4L Polyethylene Glycol (PEG) Versus 1L Polyethylene Glycol Plus Sodium Picosulfate-magnesium Citrate (SPMC) (PHASE4)
- Impact of PEG Bowel Preparation on Gut Microbiome Composition Recovery (PHASE1)
- Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing (NA)
- Technical Feasibility Evaluation of Mucosal Staining During Colon Capsule Endoscopy (CCE) Procedure in Colorectal Cancer (CRC) High Risk Population, When Using MB-MMX (NA)
- Mechanical Bowel Preparation Versus no Bowel Preparation for Esophageal Cancer Surgery (NA)
- Optimization of Intestinal Preparation in Older Patients (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- 4L PEG CI brief — competitive landscape report
- 4L PEG updates RSS · CI watch RSS
- Changhai Hospital portfolio CI
Frequently asked questions about 4L PEG
What is 4L PEG?
Who makes 4L PEG?
Is 4L PEG also known as anything else?
What drug class is 4L PEG in?
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What does 4L PEG target?
Related
- Drug class: All Osmotic laxative drugs
- Target: All drugs targeting Colon
- Manufacturer: Changhai Hospital — full pipeline
- Therapeutic area: All drugs in Gastroenterology
- Also known as: polyethylene glycol
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing