Last reviewed 2026-05-29 · How we verify

Plegisol In Plastic Container (Calcium Chloride)

Pfizer Inc. · FDA-approved approved Small molecule ✓ Verified May 2026 Quality 46/100

Plegisol In Plastic Container (generic name: Calcium Chloride) is a Electrolyte solution Small molecule drug developed by Pfizer Inc.. It is currently FDA-approved for Source of water in adults, Source of electrolytes in adults, Source of water in pediatric patients.

Provides water and electrolytes to maintain fluid balance, osmotic pressure, and electrolyte homeostasis.

Plegisol In Plastic Container is a solution containing calcium chloride, a white crystalline solid that is highly soluble in water. It is created by neutralizing hydrochloric acid with calcium hydroxide.

At a glance

Generic name	Calcium Chloride
Sponsor	Pfizer Inc.
Drug class	Electrolyte solution
Target	Electrolyte balance and fluid distribution
Modality	Small molecule
Phase	FDA-approved

Mechanism of action

Ringer's Injection is a source of water and electrolytes containing sodium, potassium, chloride, and calcium. Sodium, the major extracellular cation, controls water distribution, fluid balance, and osmotic pressure while working with chloride and bicarbonate to regulate acid-base equilibrium. Potassium, the principal intracellular cation, participates in carbohydrate utilization and protein synthesis and is critical for nerve conduction and muscle contraction, particularly cardiac function. Chloride, the major extracellular anion, follows sodium metabolism and reflects changes in acid-base balance. Calcium provides the structural framework of bones and teeth and is essential for blood clotting, normal cardiac function, and regulation of neuromuscular irritability in its ionized form.

Approved indications

Source of water in adults
Source of electrolytes in adults
Source of water in pediatric patients
Source of electrolytes in pediatric patients

Common side effects

No common side effects on file.

Drug interactions

Drugs that affect electrolyte and/or fluid balance
Potassium-sparing diuretics, ACE inhibitors, angiotensin II receptor antagonists, calcineurin inhibitors
Diuretics and drugs causing SIADH (arginine vasopressin analogs, antiepileptic, psychotropic, cytotoxic drugs)
Thiazide diuretics or vitamin D
Lithium
Digoxin

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

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Frequently asked questions about Plegisol In Plastic Container

What is Plegisol In Plastic Container?

Plegisol In Plastic Container (Calcium Chloride) is a Electrolyte solution drug developed by Pfizer Inc., indicated for Source of water in adults, Source of electrolytes in adults, Source of water in pediatric patients.

How does Plegisol In Plastic Container work?

Provides water and electrolytes to maintain fluid balance, osmotic pressure, and electrolyte homeostasis.

What is Plegisol In Plastic Container used for?

Plegisol In Plastic Container is indicated for Source of water in adults, Source of electrolytes in adults, Source of water in pediatric patients, Source of electrolytes in pediatric patients.

Who makes Plegisol In Plastic Container?

Plegisol In Plastic Container is developed and marketed by Pfizer Inc. (see full Pfizer Inc. pipeline at /company/pfizer).

What is the generic name of Plegisol In Plastic Container?

Calcium Chloride is the generic (nonproprietary) name of Plegisol In Plastic Container.

What drug class is Plegisol In Plastic Container in?

Plegisol In Plastic Container belongs to the Electrolyte solution class. See all Electrolyte solution drugs at /class/electrolyte-solution.

What development phase is Plegisol In Plastic Container in?

Plegisol In Plastic Container is FDA-approved (marketed).

What does Plegisol In Plastic Container target?

Plegisol In Plastic Container targets Electrolyte balance and fluid distribution and is a Electrolyte solution.

Drug class: All Electrolyte solution drugs
Target: All drugs targeting Electrolyte balance and fluid distribution
Manufacturer: Pfizer Inc. — full pipeline
Indication: Drugs for Source of water in adults
Indication: Drugs for Source of electrolytes in adults
Indication: Drugs for Source of water in pediatric patients

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing