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Placebo (WO3988)

Dr. August Wolff GmbH & Co. KG Arzneimittel · Phase 3 active Small molecule

Placebo produces therapeutic effects through patient expectation and the psychobiological response to treatment.

At a glance

Generic namePlacebo (WO3988)
SponsorDr. August Wolff GmbH & Co. KG Arzneimittel
ModalitySmall molecule
PhasePhase 3

Mechanism of action

Placebo works via the placebo effect, wherein a patient's belief in receiving treatment activates neurobiological pathways that can reduce symptoms and improve outcomes, independent of pharmacological activity. This involves activation of endogenous pain-relief systems, expectancy-driven neural responses, and conditioning mechanisms. The effect is particularly pronounced in conditions with subjective symptom components such as pain, nausea, and fatigue.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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