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placebo to metronidazole
placebo to metronidazole is a nitroimidazole antibiotic Small molecule drug developed by Merck Sharp & Dohme LLC. It is currently in Phase 3 development for Amoebiasis, Bacterial vaginosis, Gastrointestinal infections.
Metronidazole is an antibiotic that works by stopping the growth of bacteria and protozoa.
Metronidazole is an antibiotic that works by stopping the growth of bacteria and protozoa. Used for Amoebiasis, Bacterial vaginosis, Gastrointestinal infections.
At a glance
| Generic name | placebo to metronidazole |
|---|---|
| Sponsor | Merck Sharp & Dohme LLC |
| Drug class | nitroimidazole antibiotic |
| Modality | Small molecule |
| Therapeutic area | Gastrointestinal |
| Phase | Phase 3 |
Mechanism of action
It does this by inhibiting the synthesis of DNA and RNA in these microorganisms, ultimately leading to their death. This is achieved through the disruption of the bacterial cell's ability to produce pyrimidine nucleotides, which are essential for DNA and RNA synthesis.
Approved indications
- Amoebiasis
- Bacterial vaginosis
- Gastrointestinal infections
- Pelvic inflammatory disease
- Trichomoniasis
Common side effects
- Nausea
- Diarrhea
- Abdominal pain
- Vaginal itching
- Headache
Key clinical trials
- APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis) (PHASE2)
- Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery (NA)
- FMT for Lung and Associated-organ Rescue Efficacy in Pulmonary Infection With MDROs (NA)
- Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates (NA)
- Sea Buckthorn Aqueous Infusion Impact (NA)
- Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among Veterans (PHASE3)
- Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes (NA)
- Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- placebo to metronidazole CI brief — competitive landscape report
- placebo to metronidazole updates RSS · CI watch RSS
- Merck Sharp & Dohme LLC portfolio CI
Frequently asked questions about placebo to metronidazole
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Related
- Drug class: All nitroimidazole antibiotic drugs
- Manufacturer: Merck Sharp & Dohme LLC — full pipeline
- Therapeutic area: All drugs in Gastrointestinal
- Indication: Drugs for Amoebiasis
- Indication: Drugs for Bacterial vaginosis
- Indication: Drugs for Gastrointestinal infections
- Compare: placebo to metronidazole vs similar drugs
- Pricing: placebo to metronidazole cost, discount & access