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Placebo Suppositories
Placebo suppositories produce therapeutic effects primarily through the placebo effect, wherein inert ingredients trigger beneficial physiological responses based on patient expectation and belief.
At a glance
| Generic name | Placebo Suppositories |
|---|---|
| Sponsor | Kristina A. Butler |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Placebo suppositories contain no pharmacologically active ingredients but may elicit symptom relief or clinical improvement through psychological mechanisms including expectation, conditioning, and the natural history of disease. The rectal route of administration may enhance the perception of efficacy. Clinical benefits are typically observed in conditions with significant subjective or psychosomatic components.
Approved indications
Common side effects
Key clinical trials
- A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix (PHASE3)
- Feasibility of Intravaginal Artesunate as Adjuvant HPV & Cervical Precancer Treatment in Kenya (PHASE2)
- Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3) (PHASE2)
- Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories (PHASE3)
- Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial) (PHASE4)
- Randomized, Double-Blind Placebo-Controlled Trial to Assess Overall User Experience of a Synbiotic Vaginal Suppository (NA)
- Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (PHASE2)
- Vaginal Baclofen Suppositories in Chronic Pelvic Pain (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |