Last reviewed 2026-04-19 · How we verify

placebo oxycodone / naloxone

At a glance

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

• Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms (NA)
• Comparison Between Oxycodone and Pregabalin as Preemptive Analgesia (PHASE2, PHASE3)
• OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS) (PHASE2)
• A Randomised, Double Blind, Placebo and Active Controlled, Double Dummy,Parallel Group Study to Determine the Safety and Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Subjects With Moderate to Severe, Chronic Nonmalignant Pain (PHASE3)
• Oxycodone/Naloxone Prolonged Release (OXN PR) Compared to Placebo to Demonstrate Improvement in Symptoms of Restless Legs Syndrome (RLS) in Subjects With Moderate to Severe Idiopathic RLS With Daytime Symptoms (PHASE3)
• Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery (PHASE3)
• A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain (PHASE3)
• Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia (PHASE4)

Primary sources

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