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Placebo of aspirin
A placebo contains no active pharmaceutical ingredient and produces therapeutic effects solely through the placebo effect.
A placebo contains no active pharmaceutical ingredient and produces therapeutic effects solely through the placebo effect. Used for Control arm in clinical trials (not a therapeutic indication).
At a glance
| Generic name | Placebo of aspirin |
|---|---|
| Sponsor | Asan Medical Center |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Placebos are inert substances used as controls in clinical trials to measure the effect of expectation and psychological factors on patient outcomes. In this case, it is a placebo formulated to mimic aspirin but without the active ingredient acetylsalicylic acid. Any observed clinical benefit would be attributable to patient expectation and the mind-body response rather than pharmacological action.
Approved indications
- Control arm in clinical trials (not a therapeutic indication)
Common side effects
- Placebo effect (perceived symptom improvement)
- Nocebo effect (perceived adverse events)
Key clinical trials
- IRELAnD: Investigating the Role of Early Low-dose Aspirin in Diabetes (PHASE3)
- Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma (PHASE2)
- The Impact of Factor Xa Inhibition on Thrombosis, Platelet Activation, and Endothelial Function in Peripheral Artery Disease (PHASE4)
- The Effect and Safety of Combined Anti-platelet Treatment in Acute Ischemic Stroke Due to Large Artery Atherosclerosis (PHASE4)
- Aspirin Continuation or Interruption in Patients at Moderate Risk for Cardiovascular Events Undergoing Colonoscopy and/or Polypectomy (PHASE3)
- REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants (PHASE3)
- Effectiveness of the Eradication of Helicobacter Pylori and an Inhibitor of Pump With Proton Versus Control (PHASE4)
- COLchicine and Non-enteric Coated Aspirin in the Cardiovascular Outcomes Trial of Patients With Type 2 Diabetes (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |