Last reviewed · How we verify
Placebo matching Metformin XR
This is a placebo formulation designed to match the appearance and administration profile of Metformin XR for use as a control in clinical trials.
This is a placebo formulation designed to match the appearance and administration profile of Metformin XR for use as a control in clinical trials. Used for Control arm in phase 3 clinical trials of Metformin XR.
At a glance
| Generic name | Placebo matching Metformin XR |
|---|---|
| Sponsor | AstraZeneca |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | Phase 3 |
Mechanism of action
Placebo matching Metformin XR contains no active pharmaceutical ingredient and serves as a blinded control comparator in phase 3 trials. It is formulated to be indistinguishable from the active Metformin XR drug in terms of appearance, taste, and release characteristics, enabling proper randomized controlled trial design. This allows researchers to isolate the true effects of Metformin XR from placebo effects.
Approved indications
- Control arm in phase 3 clinical trials of Metformin XR
Common side effects
Key clinical trials
- Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction (PHASE2)
- Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes (PHASE4)
- Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy (PHASE2)
- Metformin for Fibromyalgia Symptoms (INFORM Trial) (PHASE2)
- Preventing Injured Knees From osteoArthritis: Severity Outcomes (PHASE2)
- Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD) (PHASE3)
- Metabolic Effects of Metformin Therapy in Obstructive Sleep Apnea (PHASE1, PHASE2)
- Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers. (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo matching Metformin XR CI brief — competitive landscape report
- Placebo matching Metformin XR updates RSS · CI watch RSS
- AstraZeneca portfolio CI