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Placebo gum
Placebo gum produces therapeutic effects through the patient's expectation and belief in the treatment rather than through active pharmacological ingredients.
Placebo gum produces therapeutic effects through the patient's expectation and belief in the treatment rather than through active pharmacological ingredients. Used for Clinical research control comparator, Conditions responsive to placebo effect (e.g., mild pain, anxiety).
At a glance
| Generic name | Placebo gum |
|---|---|
| Sponsor | McNeil AB |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Placebo gum is an inert formulation designed to elicit a placebo response, where symptom improvement occurs due to psychological expectation and the ritual of treatment rather than active drug mechanisms. This may involve activation of endogenous pain-relief pathways, reduction in anxiety, or other psychosomatic effects. Placebo products are typically used in clinical research settings as control comparators or in specific therapeutic contexts where the placebo effect itself is therapeutically valuable.
Approved indications
- Clinical research control comparator
- Conditions responsive to placebo effect (e.g., mild pain, anxiety)
Common side effects
- Adverse events typically limited to those from inert gum base (e.g., jaw discomfort, mild gastrointestinal effects)
Key clinical trials
- Effects of Different Caffeine Forms on Aerobic and Anaerobic Exercise Performance (NA)
- Effects of 2-Aticyto Complex and D-Ribose on Pain and Clinical Course in Patients With Fibromyalgia (NA)
- Using Nicotine to Reverse Age-related Auditory Processing Deficits (NA)
- Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients (NA)
- Single Strain Probiotic (NA)
- Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH and Its Role in Improving Oral Hygiene and Gingival Health. In Situ Randomized Double-Blind Placebo CT (PHASE1)
- Effect of Nigella Sativa Toothpaste on Salivary Biomarkers in Patients With Gingivitis (NA)
- Microbiological and Clinical Effects of Pre- and Probiotics in Non-Surgical Periodontal Therapy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo gum CI brief — competitive landscape report
- Placebo gum updates RSS · CI watch RSS
- McNeil AB portfolio CI