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Placebo, gonadotropins in step-up regimen
Gonadotropins administered in a step-up regimen stimulate the ovaries to produce multiple follicles for assisted reproductive procedures.
Placebo, a gonadotropins in step-up regimen, is currently marketed by the University of Modena and Reggio Emilia. The key composition patent is set to expire in 2028, which may provide a period of market exclusivity. However, the lack of detailed clinical trial results and revenue data poses a significant risk in assessing the drug's market performance and competitive landscape.
At a glance
| Generic name | Placebo, gonadotropins in step-up regimen |
|---|---|
| Sponsor | University of Modena and Reggio Emilia |
| Drug class | Gonadotropin |
| Target | FSH receptor, LH receptor |
| Modality | Small molecule |
| Therapeutic area | Reproductive Medicine / Fertility |
| Phase | FDA-approved |
Mechanism of action
Gonadotropins (FSH and/or hCG) are hormones that directly stimulate follicle development in the ovaries. A step-up regimen begins with a lower dose and increases incrementally based on ovarian response, aiming to achieve controlled multifollicular development while minimizing overstimulation. This approach is used in fertility treatment to obtain multiple oocytes for in vitro fertilization or other assisted reproductive technologies.
Approved indications
- Infertility in women undergoing assisted reproductive technology (ART)
- Anovulation and ovulatory disorders
Common side effects
- Ovarian hyperstimulation syndrome (OHSS)
- Injection site reactions
- Headache
- Abdominal discomfort
- Nausea
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
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