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Placebo for oral corticosteroids
A placebo contains no active pharmaceutical ingredient and produces no direct pharmacological effect.
A placebo contains no active pharmaceutical ingredient and produces no direct pharmacological effect. Used for Control arm in Phase 3 trial for oral corticosteroid-dependent condition (specific indication unknown).
At a glance
| Generic name | Placebo for oral corticosteroids |
|---|---|
| Sponsor | Ultragenyx Pharmaceutical Inc |
| Modality | Small molecule |
| Phase | Phase 3 |
Mechanism of action
Placebos are inert substances used as control comparators in clinical trials to measure the efficacy of an active drug against baseline or non-specific effects. In this Phase 3 trial context, the placebo serves as a comparator arm for evaluating an investigational treatment for oral corticosteroid-dependent conditions. Any observed clinical benefit in the placebo group would reflect natural disease progression, regression to the mean, or psychological/expectation effects rather than pharmacological action.
Approved indications
- Control arm in Phase 3 trial for oral corticosteroid-dependent condition (specific indication unknown)
Common side effects
Key clinical trials
- Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients (PHASE2)
- Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V (PHASE2)
- A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease (PHASE3)
- A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) (PHASE2)
- Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease (PHASE2)
- Effect of Preoperative Long-Acting Corticosteroids on Pain, Swelling, and Trismus After Impacted Lower Third Molar Surgery (NA)
- Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis (PHASE4)
- Evaluation of the Efficacy of Corticosteroids in Septic Arthritis in Adults (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |