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Placebo for Diazepam
A placebo contains no active pharmaceutical ingredient and produces therapeutic effects solely through psychological and psychophysiological mechanisms.
A placebo contains no active pharmaceutical ingredient and produces therapeutic effects solely through psychological and psychophysiological mechanisms. Used for Control arm in clinical trials for anxiety disorders or insomnia (not a therapeutic indication).
At a glance
| Generic name | Placebo for Diazepam |
|---|---|
| Sponsor | Institute of Mental Health, Singapore |
| Modality | Small molecule |
| Therapeutic area | Psychiatry/Neurology |
| Phase | FDA-approved |
Mechanism of action
Placebos work through expectation, conditioning, and the patient's belief in treatment, activating endogenous neurobiological pathways that can reduce symptoms. In the context of this diazepam placebo study, patients may experience anxiolytic or sedative effects through the placebo response rather than through benzodiazepine receptor modulation. The placebo effect is particularly robust for subjective symptoms like anxiety and insomnia.
Approved indications
- Control arm in clinical trials for anxiety disorders or insomnia (not a therapeutic indication)
Common side effects
Key clinical trials
- Evaluating Bone Marrow Cell Transplant for Treating Cerebral Palsy From Brain Hypoxia (PHASE2)
- Vaginal Diazepam for the Treatment of Female Pelvic Pain (PHASE2)
- Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo (PHASE3)
- Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome (NA)
- Oral Olanzapine Versus Haloperidol or Diazepam (PHASE4)
- Gabapentin Treatment of Benzodiazepine Dependence (PHASE2)
- Diazepam Use With Standard Management for Acute Low Back Pain (PHASE2, PHASE3)
- Baclofen/Diazepam Supps for Treatment of Pelvic Floor Myalgia (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo for Diazepam CI brief — competitive landscape report
- Placebo for Diazepam updates RSS · CI watch RSS
- Institute of Mental Health, Singapore portfolio CI