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Placebo Folic Acid

National Heart, Lung, and Blood Institute (NHLBI) · FDA-approved active Small molecule

Placebo Folic Acid is a Small molecule drug developed by National Heart, Lung, and Blood Institute (NHLBI). It is currently FDA-approved for Control arm in cardiovascular clinical trials (e.g., homocysteine reduction studies). Also known as: Vitamin B-9,Folison, Folic placebo, folicap.

Placebo folic acid has no active pharmacological mechanism; it serves as an inert control in clinical trials.

Placebo folic acid has no active pharmacological mechanism; it serves as an inert control in clinical trials. Used for Control arm in cardiovascular clinical trials (e.g., homocysteine reduction studies).

At a glance

Generic namePlacebo Folic Acid
Also known asVitamin B-9,Folison, Folic placebo, folicap
SponsorNational Heart, Lung, and Blood Institute (NHLBI)
ModalitySmall molecule
Therapeutic areaCardiovascular
PhaseFDA-approved

Mechanism of action

As a placebo, this formulation contains folic acid but is used in blinded studies to provide a control arm without active therapeutic effect. Folic acid itself is a B vitamin cofactor essential for nucleotide synthesis and methylation reactions, but when used as a placebo it is intended to have no measurable clinical benefit beyond baseline.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Placebo Folic Acid

What is Placebo Folic Acid?

Placebo Folic Acid is a Small molecule drug developed by National Heart, Lung, and Blood Institute (NHLBI), indicated for Control arm in cardiovascular clinical trials (e.g., homocysteine reduction studies).

How does Placebo Folic Acid work?

Placebo folic acid has no active pharmacological mechanism; it serves as an inert control in clinical trials.

What is Placebo Folic Acid used for?

Placebo Folic Acid is indicated for Control arm in cardiovascular clinical trials (e.g., homocysteine reduction studies).

Who makes Placebo Folic Acid?

Placebo Folic Acid is developed and marketed by National Heart, Lung, and Blood Institute (NHLBI) (see full National Heart, Lung, and Blood Institute (NHLBI) pipeline at /company/national-heart-lung-and-blood-institute-nhlbi).

Is Placebo Folic Acid also known as anything else?

Placebo Folic Acid is also known as Vitamin B-9,Folison, Folic placebo, folicap.

What development phase is Placebo Folic Acid in?

Placebo Folic Acid is FDA-approved (marketed).

What are the side effects of Placebo Folic Acid?

Common side effects of Placebo Folic Acid include No expected adverse events beyond those of folic acid at standard doses.

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