Last reviewed · How we verify
Placebo first BA
Placebo first BA is a bioavailability study design approach that administers placebo prior to the active drug to establish baseline pharmacokinetic parameters.
At a glance
| Generic name | Placebo first BA |
|---|---|
| Also known as | NaCl, Saline |
| Sponsor | Tampere University Hospital |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
This is a clinical trial methodology rather than a drug with a pharmacological mechanism. 'Placebo first BA' refers to a study design where subjects receive placebo in an initial period before crossing over to receive the active pharmaceutical agent, allowing researchers to measure the drug's bioavailability and pharmacokinetic properties while controlling for baseline variability.
Approved indications
Common side effects
Key clinical trials
- Effects of Akkermansia Muciniphila and Berberine Supplementation on Insulin Sensitivity in Night-shift Workers (NA)
- Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department (PHASE3)
- Effects of Sitagliptin in Individuals With Genetically Decreased DPP4 (PHASE4)
- Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial) (PHASE2)
- Safety, Tolerability, and Systemic Exposure of Apo-Si- K170A-C76 in Healthy Volunteers (PHASE1)
- Effects of β-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Biochemical Markers Concentrations (PHASE3)
- A Study to Assess the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of ASP6981 in Subjects With Schizophrenia (PHASE1)
- Comparison of Ba-Duan-Jin and Pregabalin in Patients with Fibromyalgia (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo first BA CI brief — competitive landscape report
- Placebo first BA updates RSS · CI watch RSS
- Tampere University Hospital portfolio CI