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Placebo Drink + Moxifloxacin Capsule

University of the Pacific · FDA-approved active Small molecule

Moxifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription in susceptible bacteria.

Moxifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription in susceptible bacteria. Used for Bacterial infections (respiratory tract, skin and soft tissue, intra-abdominal, complicated skin infections).

At a glance

Generic namePlacebo Drink + Moxifloxacin Capsule
SponsorUniversity of the Pacific
Drug classFluoroquinolone antibiotic
TargetDNA gyrase; Topoisomerase IV
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhaseFDA-approved

Mechanism of action

Moxifloxacin works by binding to and inhibiting bacterial DNA gyrase (in gram-negative bacteria) and topoisomerase IV (in gram-positive bacteria), enzymes essential for DNA replication and repair. This dual inhibition leads to rapid bactericidal activity against a broad spectrum of aerobic and anaerobic bacteria. The placebo drink component serves as a control vehicle in this formulation.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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