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Placebo (digestive tablet)
A placebo tablet produces therapeutic effects through the patient's psychological expectation and belief in treatment rather than through active pharmacological mechanisms.
A placebo tablet produces therapeutic effects through the patient's psychological expectation and belief in treatment rather than through active pharmacological mechanisms. Used for Functional digestive symptoms (as a control or therapeutic agent in clinical research).
At a glance
| Generic name | Placebo (digestive tablet) |
|---|---|
| Sponsor | Seoul National University Hospital |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | FDA-approved |
Mechanism of action
Placebo effects operate via neurobiological pathways including expectation-driven dopamine release, endogenous opioid activation, and autonomic nervous system modulation. In digestive complaints, placebo can reduce symptoms through reduced anxiety, altered gut-brain signaling, and enhanced parasympathetic tone. The effect is particularly pronounced in functional gastrointestinal disorders where psychological factors contribute significantly to symptom perception.
Approved indications
- Functional digestive symptoms (as a control or therapeutic agent in clinical research)
Common side effects
Key clinical trials
- 24-Week Induction Study of APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE 3) (PHASE3)
- Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH) (PHASE2)
- Evaluating the Efficacy of "Digestive Aid" in Functional Dyspepsia (NA)
- Effectiveness of Probiotics for the Prevention of Gastrointestinal Toxicity in Children with Leukemia (PHASE2)
- Zypan Functional Dyspepsia (NA)
- Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2) (PHASE3)
- Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) (PHASE2)
- Non Surgical Therapy of Periodontitis in Diabetes Patients: the Adjunctive Use of Probiotics (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |