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Placebo.
Placebo produces therapeutic effects through patient expectation and the psychobiological placebo response, rather than through a pharmacologically active ingredient.
Placebo produces therapeutic effects through patient expectation and the psychobiological placebo response, rather than through a pharmacologically active ingredient. Used for Subjective symptom relief in clinical research and therapeutic contexts (pain, nausea, fatigue).
At a glance
| Generic name | Placebo. |
|---|---|
| Sponsor | University Hospital, Bordeaux |
| Modality | Small molecule |
| Therapeutic area | Multiple (context-dependent) |
| Phase | FDA-approved |
Mechanism of action
Placebo works via psychological and neurobiological mechanisms including expectation, conditioning, and activation of endogenous pain-relief and reward pathways. The effect is particularly pronounced in conditions with subjective symptom components such as pain, nausea, and fatigue. While placebo has no direct molecular target, it can produce measurable physiological changes through mind-body interactions.
Approved indications
- Subjective symptom relief in clinical research and therapeutic contexts (pain, nausea, fatigue)
Common side effects
- Nocebo effects (adverse expectations)
- Delayed treatment of underlying condition if used as sole therapy
Key clinical trials
- Safety and Efficacy of L. Lactis CKDB001 in Subjects With Early Alzheimer's Disease (NA)
- Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure (NA)
- The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health. (NA)
- A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP) (PHASE2)
- A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases (PHASE3)
- Trial of Suvorexant for Sleep in Children With Autism (PHASE2)
- The Effect of NP-2006 on Sleep Quality and Health (NA)
- Efficacy of Nigella Sativa (Nisatol®) in Women With Borderline Blood Pressure Values or a Non-Dipper Blood Pressure Phenotype (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo. CI brief — competitive landscape report
- Placebo. updates RSS · CI watch RSS
- University Hospital, Bordeaux portfolio CI