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PIOLIN®
PIOLIN is a small molecule that acts as a selective inhibitor of the enzyme responsible for the production of a key inflammatory mediator.
PIOLIN is a small molecule that acts as a selective inhibitor of the enzyme responsible for the production of a key inflammatory mediator. Used for Treatment of rheumatoid arthritis.
At a glance
| Generic name | PIOLIN® |
|---|---|
| Also known as | RUTA GRAVEOLENS STANDARDIZED FLUID EXTRACT |
| Sponsor | Phytopharm Consulting Brazil |
| Drug class | Selective enzyme inhibitor |
| Target | COX-2 |
| Modality | Small molecule |
| Therapeutic area | Rheumatology |
| Phase | Phase 3 |
Mechanism of action
By inhibiting this enzyme, PIOLIN reduces the levels of the inflammatory mediator, thereby decreasing inflammation and associated symptoms. This mechanism is particularly relevant in the treatment of conditions characterized by chronic inflammation, such as rheumatoid arthritis.
Approved indications
- Treatment of rheumatoid arthritis
Common side effects
- Gastrointestinal upset
- Headache
- Dizziness
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PIOLIN® CI brief — competitive landscape report
- PIOLIN® updates RSS · CI watch RSS
- Phytopharm Consulting Brazil portfolio CI