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Periclor (PETRICHLORAL)

Phase 2 active Small molecule ✓ Verified May 2026

Periclor (generic name: PETRICHLORAL) is a petrichloral drug. It is currently in Phase 2 development.

Periclor works by enhancing the activity of neurotransmitters in the brain to induce relaxation and sleep.

Periclor is a small molecule with the synonyms PENTAERYTHRITOL CHLORAL, PETRICHLORAL, and PETRICLORAL.

Likelihood of approval
12.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • CNS / neurology attrition -3.0pp
    CNS drugs have historically high Phase 3 failure rates (notably in Alzheimer disease + major depression).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic namePETRICHLORAL
Drug classpetrichloral
ModalitySmall molecule
Therapeutic areaNeuroscience
PhasePhase 2

Mechanism of action

Imagine your brain is a busy city with many different streets and intersections. Periclor helps calm down the traffic by increasing the activity of certain chemical messengers, or 'cars,' that help you relax and fall asleep. This can make it easier to fall asleep and stay asleep, but it's not yet clear how it works or what its long-term effects might be.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Periclor

What is Periclor?

Periclor (PETRICHLORAL) is a petrichloral drug.

How does Periclor work?

Periclor works by enhancing the activity of neurotransmitters in the brain to induce relaxation and sleep.

What is the generic name of Periclor?

PETRICHLORAL is the generic (nonproprietary) name of Periclor.

What drug class is Periclor in?

Periclor belongs to the petrichloral class. See all petrichloral drugs at /class/petrichloral.

What development phase is Periclor in?

Periclor is in Phase 2.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing