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PET Scan with [18F] VAT
[18F] VAT is a fluorine-18 labeled positron emission tomography (PET) imaging agent that binds to vascular adhesion molecules to visualize inflammation and vascular pathology.
[18F] VAT is a fluorine-18 labeled positron emission tomography (PET) imaging agent that binds to vascular adhesion molecules to visualize inflammation and vascular pathology. Used for PET imaging of vascular inflammation and atherosclerotic disease, Assessment of endothelial activation in cardiovascular disease.
At a glance
| Generic name | PET Scan with [18F] VAT |
|---|---|
| Sponsor | Stony Brook University |
| Drug class | PET imaging agent / Radiopharmaceutical |
| Target | Vascular adhesion molecules (VAM) |
| Modality | Small molecule |
| Therapeutic area | Diagnostic Imaging / Nuclear Medicine |
| Phase | FDA-approved |
Mechanism of action
[18F] VAT (likely a vascular adhesion molecule targeting agent) is a radiopharmaceutical designed for PET imaging that uses fluorine-18 as the radioactive tracer. It accumulates at sites of vascular inflammation and endothelial activation by binding to adhesion molecules expressed on activated endothelium. This allows non-invasive visualization and quantification of inflammatory vascular disease burden.
Approved indications
- PET imaging of vascular inflammation and atherosclerotic disease
- Assessment of endothelial activation in cardiovascular disease
Common side effects
- Radiation exposure
- Allergic reaction to tracer
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PET Scan with [18F] VAT CI brief — competitive landscape report
- PET Scan with [18F] VAT updates RSS · CI watch RSS
- Stony Brook University portfolio CI