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Permethrin 1% rinse
Permethrin 1% rinse works by killing or repelling insects and other arthropods through its insecticidal properties.
Permethrin 1% rinse works by killing or repelling insects and other arthropods through its insecticidal properties. Used for Treatment and prevention of head lice infestations, Treatment and prevention of scabies infestations.
At a glance
| Generic name | Permethrin 1% rinse |
|---|---|
| Also known as | Nix Creme Rinse |
| Sponsor | Sun Pharmaceutical Industries, Inc. |
| Drug class | pyrethroid |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 3 |
Mechanism of action
Permethrin is a synthetic pyrethroid that acts on the nervous system of insects, causing paralysis and death. It is used in various formulations, including shampoos, lotions, and rinses, for the treatment and prevention of infestations.
Approved indications
- Treatment and prevention of head lice infestations
- Treatment and prevention of scabies infestations
Common side effects
- Skin irritation
- Eye irritation
Key clinical trials
- A Study to Evaluate the Efficacy and Safety of a Leave-in Spray in Subjects With Head Lice Infestation (PHASE4)
- Sulfur vs. Different Regimes of Permethrin for Scabies (PHASE3)
- Veron Scabies Education and Eradication Program (NA)
- Cocamide DEA vs Permethrin for Head Lice (PHASE3)
- Efficacy and Safety of Licefreee Spray Against Nix 1% Permethrin (NA)
- Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice (PHASE3)
- Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice (PHASE3)
- Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Permethrin 1% rinse CI brief — competitive landscape report
- Permethrin 1% rinse updates RSS · CI watch RSS
- Sun Pharmaceutical Industries, Inc. portfolio CI