Last reviewed · How we verify
Percocet
At a glance
| Generic name | Percocet |
|---|---|
| Also known as | oxycodone/acetominophen, Oxycodone/APAP(acetaminophen), Oxycodone / Paracetamol |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
Approved indications
Boxed warnings
- WARNING: SERIOUS AND LIFE-THREATENING RISKS FROM USE OF PERCOCET Addiction, Abuse, and Misuse Because the use of PERCOCET exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death, assess each patient’s risk prior to prescribing and reassess all patients regularly for the development of these behaviors and conditions [see WARNINGS ] . Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression
Common side effects
- Nausea
- Vomiting
- Drowsiness
- Sedation
- Dizziness
- Lightheadedness
- Constipation
- Pruritus
- Euphoria
- Dysphoria
- Headache
- Increased sweating
Serious adverse events
- Respiratory depression
- Respiratory arrest
- Apnea
- Hepatic necrosis
- Hepatic failure
- Anaphylaxis
- Serotonin syndrome
- Adrenal insufficiency
- Seizures
- Renal failure
Key clinical trials
- Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction (PHASE2, PHASE3)
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery (NA)
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology (NA)
- A Study on Reducing Opioid Use After Minimally Invasive Ankle Surgery (NA)
- The Efficacy and Safety of Liposomal Bupivacaine for Rhomboid Intercostal Nerve Block in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery (NA)
- Post-operative Pain Management in Children With Supracondylar Humerus Fractures (PHASE4)
- Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery (PHASE4)
- SCHF Post-Op Study Between Opioid and Non-Opioid Pain Management (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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