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Peptavlon (PENTAGASTRIN)
Peptavlon, also known as pentagastrin, is a small molecule drug that targets the gastrin/cholecystokinin type B receptor. Originally developed by Wyeth Ayerst, it was FDA approved in 1974 for certain indications. As an off-patent drug, there are currently no generic manufacturers. Peptavlon works by stimulating the gastrin/cholecystokinin type B receptor, which plays a role in gastric acid secretion. Its commercial status and key safety considerations are not well-documented.
At a glance
| Generic name | PENTAGASTRIN |
|---|---|
| Sponsor | Wyeth Ayerst |
| Drug class | pentagastrin |
| Target | Gastrin/cholecystokinin type B receptor, Cholecystokinin receptor type A, Gastrin/cholecystokinin type B receptor |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
| First approval | 1974 |
Approved indications
Common side effects
Key clinical trials
- A New Method for Determining Gastric Acid Output Using a Wireless Capsule
- Effect of Repeated Doses of YF476 on Stomach Acidity (PHASE1)
- Effect of Single Doses of YF476 on Stomach Acidity (PHASE1)
- An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD) (PHASE4)
- Open, Randomized, Two Way Crossover 40mg, Orally and Intravenously (PHASE4)
- Open, Randomized, Two Way Crossover Study Comparing the Effect of Esomeprazole Adminstered Orally and iv (PHASE4)
- Diagnosis and Treatment of Pheochromocytoma
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Peptavlon CI brief — competitive landscape report
- Peptavlon updates RSS · CI watch RSS