Last reviewed · How we verify
PEG solution
PEG solution acts as an osmotic laxative that draws water into the intestinal lumen to promote bowel evacuation.
PEG solution is an osmotic laxative that draws water into the intestinal lumen to promote bowel evacuation. Used for Bowel preparation prior to colonoscopy or other gastrointestinal procedures, Constipation management.
At a glance
| Generic name | PEG solution |
|---|---|
| Also known as | Meroken New, PEG solution, Polyethylene glycol 3350, Pegasys®, PEGASYS® |
| Sponsor | Rabin Medical Center |
| Drug class | Osmotic laxative |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | FDA-approved |
Mechanism of action
Polyethylene glycol (PEG) is a non-absorbable polymer that creates an osmotic gradient in the gastrointestinal tract. Water is retained in the bowel lumen, softening stool and increasing intestinal motility to facilitate bowel cleansing and evacuation. It is commonly used for bowel preparation prior to colonoscopy or other GI procedures.
Approved indications
- Bowel preparation prior to colonoscopy or other gastrointestinal procedures
- Constipation management
Common side effects
- Nausea
- Abdominal bloating or distension
- Abdominal cramping
- Vomiting
Key clinical trials
- A Study to Evaluate the Pharmacokinetics, Safety, and Effectiveness of Certolizumab Pegol in Children With Moderate to Severe Chronic Plaque Psoriasis (PHASE3)
- A Study in Healthy Men to Find Out How BI 425809 is Taken up and Handled by the Body (PHASE1)
- Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma (PHASE3)
- Whatsapp Based Patient Education to Improve Bowel Preparation for Colonoscopy (NA)
- A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy (PHASE3)
- Exploring the Clinical Value of an AI-Assisted Patient Self-Assessment App for Bowel Preparation: A Multicenter Study (NA)
- Pre-packaged Low-residue Diet for Bowel Preparation in Patients With Inflammatory Bowel Disease (NA)
- Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PEG solution CI brief — competitive landscape report
- PEG solution updates RSS · CI watch RSS
- Rabin Medical Center portfolio CI